Table 3.
Selected Outcome Parameters at 8 and 16 weeks.
| Outcomes | 8 weeks |
16 weeks |
||||
|---|---|---|---|---|---|---|
| Mindful walking | Walking | P-value | Mindful walking | Walking | P-value | |
| mean (95% CI) | mean (95% CI) | mean (95% CI) | mean (95% CI) | |||
| n = 24* | n = 27* | n = 24* | n = 27* | |||
| WHOQOL-BREF † | ||||||
| Physical domain † (MCID 7.7%) | 68.2 (63.1-73.3) | 68.0 (63.0-73.0) | .958 | 66.1 (60.9-71.3) | 64.9 (59.9-69.8) | .721 |
| Psychological domain † (MCID 6.3%) | 65.9 (60.7-71.2) | 65.0 (59.9-70.2) | .796 | 64.0 (57.7-70.2) | 59.8 (53.8-65.7) | .312 |
| Social Relationships domain † (MCID 6.4%) | 66.0 (59.2-72.9) | 64.2 (57.7-70.7) | .691 | 72.0 (62.2-81.9) | 58.7 (49.6-67.7) | .044 |
| Environment domain † (MCID 5.7%) | 74.8 (70.9-78.8) | 74.0 (70.1-77.9) | .764 | 74.5 (68.5-80.5) | 69.9 (64.2-75.6) | .255 |
| Overall perception of life and health (Question 1+2) † (MCID 8.8%) | 65.4 (57.1-73.7) | 61.6 (53.6-69.6) | .491 | 61.4 (53.7-69.2) | 59.4 (52.2-66.6) | .686 |
| FACT-G (MCID ≥ 6 points) | ||||||
| Total score † | 76.0 (71.5-80.5) | 73.0 (68.5-77.4) | .328 | 72.7 (68.2-77.3) | 68.7 (64.3-73.0) | .188 |
| Physical well-being † | 20.9 (19.2-22.7) | 20.4 (18.7-22.1) | .667 | 19.5 (17.8-21.3) | 20.7 (19.1-22.3) | .307 |
| Social/Family well-being † | 20.3 (18.6-22.1) | 19.0 (17.3-20.6) | .244 | 19.2 (17.4-21.1) | 16.3 (14.6-18.0) | .019 |
| Emotional well-being † | 17.3 (16.2-18.4) | 16.8 (15.7-17.9) | .509 | 16.9 (15.7-18.1) | 16.2 (15.1-17.3) | .373 |
| Functional well-being † | 17.2 (15.4-19.0) | 16.2 (14.5-18.0) | .437 | 16.6 (15.0-18.3) | 15.5 (13.9-17.0) | .296 |
| CFS-D | ||||||
| Total score ‡ | 24.3 (20.8-27.8) | 25.5 (22.1-28.8) | .63 | 25.9 (22.6-29.2) | 26.5 (23.4-29.6) | .794 |
| Physical fatigue subscale ‡ | 11.1 (9.3-12.9) | 11.5 (9.8-13.2) | .722 | 11.5 (9.8-13.2) | 11.8 (10.2-13.4) | .788 |
| Affective fatigue subscale ‡ | 5.3 (4.3-6.3) | 4.9 (3.9-5.9) | .565 | 5.7 (4.9-6.6) | 5.1 (4.3-5.9) | .314 |
| Cognitive fatigue subscale ‡ | 7.8 (6.7-9.0) | 8.5 (7.3-9.6) | .411 | 8.7 (7.4-10.0) | 8.9 (7.6-10.1) | .833 |
| PSQ | ||||||
| Overall score⁺ | 45.3 (40.5-50.1) | 45.4 (40.8-50.0) | .972 | 47.7 (42.7-52.7) | 48.6 (43.9-53.2) | .796 |
| Worries subscale⁺ | 37.7 (31.1-44.3) | 42.2 (35.8-48.5) | .314 | 41.2 (33.3-49.1) | 42.9 (35.5-50.2) | .74 |
| Tension subscale⁺ | 44.6 (38.2-51.0) | 47.2 (41.0-53.3) | .549 | 45.6 (39.8-51.3) | 51.3 (45.9-56.6) | .135 |
| Joy subscale⁺ | 47.1 (38.6-55.5) | 51.6 (43.7-59.5) | .434 | 42.0 (35.0-49.0) | 46.4 (40.1-52.8) | .338 |
| Demands subscale⁺ | 44.4 (39.3-49.6) | 44.3 (39.4-49.3) | .978 | 45.5 (39.8-51.1) | 47.1 (41.8-52.4) | .66 |
Means with 95% CI adjusted for baseline value and stratification variables and P-values.
Abbreviations: CI, confidence interval; P, P-value for treatment effect. WHOQOL-BREF, World Health Organization Quality of Life Assessment; FACT-G, functional assessment of cancer therapy-general; CFS-D, Cancer Fatigue Scale; PSQ, Perceived Stress Questionnaire.
*
Number of randomized patients; number of patients in analyses may vary, see Figure 1.
†
Higher values indicate better quality of life.
‡
Lower values indicate less suffering of fatigue.
⁺
Higher values indicate high level of perceived stress