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. 2021 Dec 5;70(2):151–168. doi: 10.1369/00221554211061359

Figure 2.

Figure 2.

Differential levels of ECM in fimbriae of benign vs STIC patients. (A) Representative multispectral staining for DNA (DAPI), P53, and ECM components: type I collagen (Coll I, red), type III collagen (Coll III, green), type IV collagen (Coll IV, blue), and pan-laminin (Lam, magenta) from a benign sample and non-STIC and STIC region from an STIC patient. (B) Representative multispectral staining for DNA (DAPI), P53, and ECM components: FN (red), HA (green), HSPG2 (blue), and VCAN (magenta) from a benign sample and non-STIC and STIC region from an STIC patient. Scale bar = 100 µm. Abbreviations: ECM, extracellular matrix; STIC, serous intraepithelial carcinoma; FN, fibronectin; HA, hyaluronan; HSPG2, perlecan; VCAN, versican; DAPI, 4′,6-diamidino-2-phenylindole.