Table 5.
Univariate Cox regression analysis of RFS
| Factor | No. of patients | No. of events | 5-year RFS (%) | Univariable analysis | ||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | ||||
| Agea, years | ||||||
| < 28 | 49 | 1 | 98.0 | Reference | ||
| ≥ 28 | 25 | 5 | 80.0 | 8.61 | (1.1–73.8) | 0.04 |
| Tumor diameterb | ||||||
| < 10 cm | 50 | 1 | 98.0 | Reference | ||
| ≥ 10 cm | 24 | 5 | 79.0 | 9.3 | (1.12–79.6) | 0.042 |
| Invasion to adjacent organs | ||||||
| No | 65 | 3 | 91.8 | Reference | ||
| Yes | 9 | 3 | 58.3 | 7.45 | (1.5–36.9) | 0.014 |
| Lymph node metastasis (pN) | ||||||
| Absent | 70 | 4 | 91.0 | Reference | ||
| Present | 4 | 2 | 0.0 | 16.8 | (2.96–94.9) | 0.001 |
| AJCC stage | ||||||
| I–II | 72 | 5 | 93.0 | Reference | ||
| III | 2 | 1 | 50.0 | 10.1 | (1.2–90.9) | 0.03 |
RFS, recurrence-free survival; HR, Hazard ratio; CI, confidence interval; AJCC, American joint committee on cancer
aAt the date of surgery
bTumor diameter in centimeters