Fig. 3.

BI853520 inhibits cell proliferation and colony formation abilities in ovarian cancer cells. A, B Proliferation of SKOV3 and OVCAR3 cells was measured using MTT at different concentrations of BI853520 for 12 h. C, D Clonogenic ability of SKOV3 and OVCAR3 cells was measured using colony formation assay at different concentrations of BI853520 for 12 h. E, F Clonogenic ability of SKOV3 and OVCAR3 cells was measured using soft agar assay following treatment with BI853520 for 12 h. The data were presented as mean ± SD of three independent experiments. **P < 0.01