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. 2021 Aug 30;12:29. doi: 10.1007/s12672-021-00425-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — BI853520 attenuates cell migration and invasion in ovarian cancer cells. A, B The effect of BI853520 on cell migration in ovarian cancer cells was measured using transwell migration assays. C, D The effect of BI853520 on cell invasion in ovarian cancer cells was measured using transwell invasion assays. E, F Adhesion assay and wound healing assays were performed to detect cell adhesion and migration in SKOV3 and OVCAR3 cells. The data were presented as mean ± SD of three independent experiments. *P < 0.05, **P < 0.01