Fig. 6.
HOXC10 knockdown inhibited tumor growth and lung metastasis of melanoma in mice. a The weight and volume of tumor xenografts in Control, shNC and shHOXC10-2# groups were measured. b Cell apoptosis in tumor tissues in Control, shNC and shHOXC10-2# groups were assessed by TUNEL staining. c The expression of HOXC10, Slug, YAP and TAZ in Control, shNC and shHOXC10-2# groups was estimated through IHC staining. d HE staining was performed to estimate the number of metastases in lung tissues in Control, shNC and shHOXC10-2# groups. **P < 0.01 vs. shNC