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Pharmacokinetics of atazanavir (ATV) in mice. Swiss–Webster mice at 8–15 weeks of age were orally treated with 60 mg/kg of ATV. (A) At indicated time points, concentration of ATV was measured in the plasma and in the lungs. The insert in panel A represents the pharmacokinetic parameters in the plasma. (B) The area under the curve (AUC) for the anatomical compartments were registered.
