Table 3.
Correlation between biochemical markers of inflammation and hypotension-related outcomes.
| NGAL | NSE | HIF-1α | S100B | Acetyl-CoA | hs Cardiac Troponin | LOOH | GSH | Hypotensive Episodies | |
|---|---|---|---|---|---|---|---|---|---|
| NGAL | 1.000 | - | - | - | - | - | - | - | - |
| NSE | 0.238 | 1.000 | - | - | - | - | - | - | - |
| HIF-1α | −0.284 | −0.369 * | 1.000 | - | - | - | - | - | - |
| S100B | 0.036 | 0.258 | −0.022 | 1.000 | - | - | - | - | - |
| Acetyl-CoA | −0.540 ** | −0.241 | −0.426 ** | 0.123 | 1.000 | - | - | - | - |
| Hs Cardiac Troponin | 0.356 * | 0.337 * | −0.304 | 0.030 | −0.391 * | 1.000 | - | - | - |
| LOOH | −0.136 | −0.103 | −0.40 | −0.258 | −0.010 | −0.040 | 1.000 | - | - |
| GSH | 0.041 | −0.213 | 0.253 | −0.283 | 0.114 | −0.398 ** | −0.099 | 1.000 | - |
| Hypotensive Episodies | 0.181 | 0.207 | −0.104 | 0.584 ** | −0.027 | 0.088 | −0.133 | −0.132 | 1.000 |
| Absolute time of hypotension | 0.288 | 0.159 | −0.133 | −0.628 ** | −0.111 | −0.138 | −0.121 | −0.164 | 0.883 ** |
| Relative time of hypotension | 0.278 | 0.118 | −0.148 | 0.612 ** | −0.096 | 0.127 | −0.199 | −0.179 | 0.880 ** |
| Time-weighted average of hypotension | 0.316 * | 0.093 | −0.150 | 0.575 ** | −0.153 | 0.174 | −0.160 | −0.170 | 0.820 ** |
* p < 0.05 (2-tailed) Mann-Whitney U test; ** p < 0.001 (2 tailed), Mann-Whitney U test. HIF: hypoxia inducible factor; GSH: reduced glutathione; LOOH: lipid hydroperoxide; NGAL: neuthrophil gelatinase-associated lipocalin; NSE: neuron-specific enolase.