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. 2021 Dec 29;15(1):43. doi: 10.3390/ph15010043

Table 4.

Results of Mixed Model ANOVAs Examining Change in Primary and Secondary Outcomes by Illness Onset Status (N = 188).

Outcome Variable F-Statistic (p-Value)
VAS Composite
Treatment
Treatment * Group
204.57 (<0.001)
1.57 (0.212)
VAS 1. Energy
Treatment
Treatment * Group
172.22 (<0.001)
0.26 (0.614)
VAS 2. Sleep
Treatment
Treatment * Group
113.03 (<0.001)
2.77 (0.098)
VAS 3. Pain
Treatment
Treatment * Group
31.47 (<0.001)
0.33 (0.567)
VAS 4. Well-Being
Treatment
Treatment * Group
168.03 (<0.001)
2.03 (0.156)
VAS 5. Mental Clarity
Treatment
Treatment * Group
104.74 (<0.001)
1.49 (0.224)
VAS 6. Stamina
Treatment
Treatment * Group
103.65 (<0.001)
2.37 (0.125)

Note: VAS: Visual Analogue Scale. Group: Onset with viral illness—yes (n = 76), no (n = 112). The “*” notation reflects “treatment times group.” This interaction term (treatment X group) provides an estimate of whether the effect of treatment in one group is statistically different from the treatment effect in another group.