Table 3.
Change | % Change | |||||
---|---|---|---|---|---|---|
Week | PRPr | CS | p-Value | PRPr | CS | p-Value |
VAS | ||||||
4 | −19.0 ± 21.3 | −34.9 ± 20.1 | 0.15 | −29.4 ± 37.0 | −57.6 ± 31.2 | 0.13 |
8 | −30.9 ± 22.7 | −26.3 ± 29.8 | 0.73 | −48.2 ± 34.9 | −41.7 ± 54.5 | 0.78 |
12 (4) | −38.3 ± 19.6 | −32.8 ± 13.4 | 0.56 | −60.1 ± 31.9 | −56.4 ± 22.0 | 0.81 |
16 (8) | −47.9 ± 21.2 | −33.3 ± 13.4 | 0.18 | −74.2 ± 33.5 | −57.3 ± 22.5 | 0.30 |
20 (12) | −45.4 ± 26.3 | −29.8 ± 12.8 | 0.64 | −67.5 ± 37.3 | −68.7 ± 20.3 | 0.94 |
32 (26) | −56.8 ± 20.2 | −36.8 ± 17.1 | 0.10 | −84.2 ± 23.8 | −66.6 ± 28.6 | 0.25 |
60 (52) | −53.4 ± 24.7 | −36.4 ± 23.7 | 0.25 | −78.2 ± 33.2 | −61.0 ± 37.9 | 0.41 |
ODI (%) | ||||||
4 | −8.2 ± 9.5 | −7.2 ± 8.4 | 0.83 | −20.4 ± 27.1 | −28.5 ± 38.0 | 0.63 |
8 | −14.5 ± 11.6 | −7.7 ± 8.9 | 0.22 | −37.7 ± 31.9 | −31.0 ± 41.1 | 0.72 |
12 (4) | −17.9 ± 13.2 | −11.2 ± 7.8 | 0.30 | −46.5 ± 33.4 | −37.1 ± 34.4 | 0.61 |
16 (8) | −23.6 ± 14.9 | −11.9 ± 7.3 | 0.10 | −62.1 ± 30.6 | −39.0 ± 32.2 | 0.19 |
20 (12) | −21.9 ± 13.4 | −12.7 ± 6.1 | 0.14 | −58.9 ± 31.1 | −43.4 ± 32.1 | 0.37 |
32 (26) | −26.9 ± 13.1 | −14.5 ± 10.8 | 0.14 | −74.8 ± 27.9 | −45.9 ± 41.1 | 0.18 |
60 (52) | −26.6 ± 14.8 | −13.9 ± 9.7 | 0.12 | −76.0 ± 37.6 | −42.4 ± 31.5 | 0.13 |
RDQ | ||||||
4 | −2.2 ± 5.9 | −2.3 ± 4.2 | 0.95 | −25.6 ± 97.1 | −38.0 ± 58.4 | 0.27 |
8 | −3.4 ± 6.7 | −1.7 ± 4.2 | 0.58 | −39.5 ± 85.8 | −32.8 ± 58.5 | 0.54 |
12 (4) | −6.9 ± 6.4 | −1.6 ± 3.6 | 0.13 | −54.8 ± 67.5 | −31.0 ± 47.8 | 0.51 |
16 (8) | −6.6 ± 6.1 | −1.7 ± 2.9 | 0.10 | −56.7 ± 63.7 | −25.6 ± 43.2 | 0.32 |
20 (12) | −6.7 ± 6.2 | −2.3 ± 4.6 | 0.17 | −65.7 ± 35.4 | −32.8 ± 56.1 | 0.18 |
32 (26) | −8.5 ± 5.3 | −3.4 ± 4.0 | 0.09 | −88.0 ± 23.5 | −42.1 ± 45.1 | 0.03 * |
60 (52) | −8.8 ± 5.0 | −4.2 ± 4.5 | 0.13 | −92.8 ± 14.1 | −49.6 ± 44.4 | 0.10 |
Change (time points − baseline) and % change ([time points − baseline]/baseline × 100) in visual analog scale (VAS), Oswestry Disability Index (ODI) [26], and Roland-Morris Disability Questionnaire (RDQ) [27,28] until 60 weeks after the injection of the platelet-rich plasma releasate (PRPr) or corticosteroid (CS). Number in parentheses indicates weeks after the optional injection. Data were expressed as means ± standard deviation (SD). * p < 0.05 between the groups.