Table 6.
Comparison of specificity, sensitivity and ppv scores for aneuploidies between NIFTY and NIPS tests.
| Chromosomal Abnormality | Sensitivity | Specificity | PPV 1 | ||||
|---|---|---|---|---|---|---|---|
| NIFTY BGI |
NIPS INVITAE |
NIFTY BGI |
NIPS INVITAE |
NIFTY BGI |
NIPS INVITAE |
Present study |
|
| Trisomy 21 | 99.17% | 99.99% | 99.95% | 99.89% | 92.19% | 92.89 | 100% |
| Trisomy 18 | 98.24%, | 99.99% | 99.95% | 99.99% | 76.61% | 89.11 | 66.66% |
| Trisomy 13 | >99.9% | 99.99% | 99.96% | 99.69% | 32.84% | 73.54 | 0% |
| Monosomy X | >99.9% | 99.99% | - | 99.89% | 40% | 69.15 | 0% |
PPV 1, Positive predictive value.