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. 2022 Jan 8;12(1):75. doi: 10.3390/jpm12010075

Figure 1.

Figure 1

Performance of the best performing childhood asthma PRS in the IOWBC. Subfigures evaluate the best childhood asthma PRS developed in the IOWBC consisted of 105-SNPs (p-value < 0.047). (A) ROC curve demonstrating the discriminative ability of the 105-SNP PRS, with 95% confidence intervals calculated from 2000 bootstrapped samples (in blue). (B) Quantile plot illustrating the risk of a school-age asthma diagnosis at age 10 across four PRS quantiles (odds ratio +/− 95% confidence intervals with respect to individuals with a PRS in the lowest quartile).