Table 3.
Animals Immunized with BGs/Antigen | Guinea Pigs | Mice | ||
---|---|---|---|---|
LD50, CFU * | II ** | LD50, CFU | II | |
…. | 147 37 ÷ 584 |
4.9 × 101 | 32 8 ÷ 126 |
4.6 × 100 |
Y-K | 6813 2154 ÷ 27123 |
2.3 × 103 | 22 5 ÷ 86 |
3 × 100 |
E-Y-K | 146,780 36,869 ÷ 926,119 |
4.9 × 104 | 22 5 ÷ 86 |
3 × 100 |
S-R-Rz | 68 17 ÷ 271 |
2.3 × 101 | 15 4 ÷ 58 |
2 × 100 |
E-S-R-Rz | 147 37 ÷ 584 |
4.9 × 101 | 46 12 ÷ 233 |
6.6 × 100 |
F1 ** | 316 79 ÷ 1259 |
1.0 × 102 | 100,000 25,119 ÷ 630,957 |
1.4 × 104 |
PBS | 3 1 ÷ 13 |
1 × 100 | 7 2 ÷ 27 |
1 × 100 |
* Values are given as means ±95% confidence intervals. ** The ability of BGs to protect an animal from death after administration of a high dose of a virulent wild type strain, designated Immunity Index (II) was calculated as the ratio: II = LD50imm/LD50veh.