Table 1.
Drug Name (Generic) | Drug Type | Benefits | Disadvantages | Representative Clinical Trials |
---|---|---|---|---|
Beclomethasone dipropionate [36] | Inhaled corticosteroid | Reduces airway swelling | Dry mouth, irritated throat, voice changes |
NCT02040766 NCT03834012 NCT00497237 NCT02513160 |
Fluticasone propionate [35] | Inhaled corticosteroid | Prevents allergic reactions | Nasal dryness, nausea, vomiting |
NCT02175771 NCT02139644 NCT02301975 NCT02980133 |
Budesonide [37] | Inhaled corticosteroid | Reduces airway swelling | Dysphonia, oropharyngeal candidiasis |
NCT01676987 NCT05152355 NCT01070888 NCT00509028 |
Ciclesonide [35] | Inhaled corticosteroid | Reduces airway swelling | Dysphonia, oropharyngeal candidiasis |
NCT03839433 NCT00163293 NCT01455194 NCT00305461 |
Fluticasone furoate [35] | Inhaled corticosteroid | Reduces airway swelling | Dysphonia, oropharyngeal candidiasis |
NCT01159912 NCT02502734 NCT01165138 NCT00649025 |
Mometasone [35] | Inhaled corticosteroid | Reduces airway swelling | Dysphonia, oropharyngeal candidiasis |
NCT00556673 NCT02415179 NCT01555151 NCT01210170 |
Tiotropium [38] | Long acting muscarinic antagonist | Bronchodilator | Dry mouth, constipation |
NCT03964220 NCT00557700 NCT02676089 NCT01340209 NCT00776984 |
Theophylline [39] | Xanthine Derivative | Relaxes airway muscles | Nausea, abdominal pain, headache, diarrhea |
NCT01684683 NCT00119496 NCT00756418 NCT00000578 |
Salmeterol xinafoate [36] | Long acting beta agonist |
Prevents bronchoconstriction | Hives, headache, blurred vision |
NCT02260492 NCT03461627 NCT04564456 NCT03535870 |
Pranlukast hydrate [40] | Leukotriene receptor antagonist | Prevents bronchospasm | Headache, abdominal or stomach pain, cough, dental pain |
NCT03826485 |
Montelukast sodium [40] | Leukotriene receptor antagonist | Prevents bronchospasm | Numbness, pain in the arms or legs, sinus pain |
NCT00140881 NCT00157937 NCT00092989 NCT00636207 |
Mepolizumab [41] | Antibody derivative | Prevents airway swelling | Pain at injection site, headache, rash |
NCT02281318 NCT01691521 NCT02555371 NCT02654145 |
Reslizumab [42] | Antibody derivative | Anti-eosinophilic activity | Pain at injection site, headache |
NCT03074942 NCT02452190 NCT00587288 NCT03052725 |
Benralizumab [43] | Antibody derivative | Anti-eosinophilic activity | Pain at injection site, headache |
NCT02322775 NCT02869438 NCT02075255 NCT02814643 |
Omalizumab [44] | Anti-IgE antibody | Prevents allergic reaction | Itching, bruising, redness, pain, or swelling at the injection site |
NCT00314574 NCT01922037 NCT02654145 NCT00046748 |