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. 2021 Dec 31;14(1):92. doi: 10.3390/pharmaceutics14010092

Table 1.

Representative Conventional Drugs for Asthma.

Drug Name (Generic) Drug Type Benefits Disadvantages Representative Clinical Trials
Beclomethasone dipropionate [36] Inhaled corticosteroid Reduces airway swelling Dry mouth, irritated throat, voice changes NCT02040766
NCT03834012
NCT00497237
NCT02513160
Fluticasone propionate [35] Inhaled corticosteroid Prevents allergic reactions Nasal dryness, nausea, vomiting NCT02175771
NCT02139644
NCT02301975
NCT02980133
Budesonide [37] Inhaled corticosteroid Reduces airway swelling Dysphonia, oropharyngeal candidiasis NCT01676987
NCT05152355
NCT01070888
NCT00509028
Ciclesonide [35] Inhaled corticosteroid Reduces airway swelling Dysphonia, oropharyngeal candidiasis NCT03839433
NCT00163293
NCT01455194
NCT00305461
Fluticasone furoate [35] Inhaled corticosteroid Reduces airway swelling Dysphonia, oropharyngeal candidiasis NCT01159912
NCT02502734
NCT01165138
NCT00649025
Mometasone [35] Inhaled corticosteroid Reduces airway swelling Dysphonia, oropharyngeal candidiasis NCT00556673
NCT02415179
NCT01555151
NCT01210170
Tiotropium [38] Long acting muscarinic antagonist Bronchodilator Dry mouth, constipation NCT03964220
NCT00557700
NCT02676089
NCT01340209
NCT00776984
Theophylline [39] Xanthine Derivative Relaxes airway muscles Nausea, abdominal pain, headache, diarrhea NCT01684683
NCT00119496
NCT00756418
NCT00000578
Salmeterol xinafoate [36] Long acting beta
agonist
Prevents bronchoconstriction Hives, headache, blurred vision NCT02260492
NCT03461627
NCT04564456
NCT03535870
Pranlukast hydrate [40] Leukotriene receptor antagonist Prevents bronchospasm Headache, abdominal or stomach pain, cough, dental pain NCT03826485
Montelukast sodium [40] Leukotriene receptor antagonist Prevents bronchospasm Numbness, pain in the arms or legs, sinus pain NCT00140881
NCT00157937
NCT00092989
NCT00636207
Mepolizumab [41] Antibody derivative Prevents airway swelling Pain at injection site, headache, rash NCT02281318
NCT01691521
NCT02555371
NCT02654145
Reslizumab [42] Antibody derivative Anti-eosinophilic activity Pain at injection site, headache NCT03074942
NCT02452190
NCT00587288
NCT03052725
Benralizumab [43] Antibody derivative Anti-eosinophilic activity Pain at injection site, headache NCT02322775
NCT02869438
NCT02075255
NCT02814643
Omalizumab [44] Anti-IgE antibody Prevents allergic reaction Itching, bruising, redness, pain, or swelling at the injection site NCT00314574
NCT01922037
NCT02654145
NCT00046748