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. 2022 Jan 14;23(2):904. doi: 10.3390/ijms23020904

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The distinct DC subsets with their respective surface markers (human and mouse) and primary functions. Markers can vary across tissues and depend on the physiological setting. cDC1, type 1 classical/conventional dendritic cell; cDC2, type 2 classical/conventional dendritic cell; pDC, plasmacytoid dendritic cell; moDC, monocyte-derived dendritic cell; BTLA, B and T cell lymphocyte attenuator; CADM1, cell adhesion molecule 1; CLEC9A, C-type-lectin 9A; BDCA3, blood dendritic cell antigen 3; XCR1, XC chemokine receptor 1; CLEC10A, C-type-lectin 10A; BDCA1, blood dendritic cell antigen 1; IL3Rα, interleukin 3Rα; BDCA2, blood dendritic cell antigen 2; CLEC4C, C-type-lectin C4; BDCA4, blood dendritic cell antigen 4; Siglec-H, sialic acid-binding immunoglobulin-like lectin-H; CCR2, C-C motif chemokine receptor 2; FcγR1, Fc-gamma receptor 1; FcγR3, Fc-gamma receptor 3.