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. 2022 Jan 8;20(1):58. doi: 10.3390/md20010058

Table 6.

Antioxidant marine xanthone.

Name Activity Source Ref.
1,4,7-Trihydroxy-6-methylxanthone (15) DPPH (IC50 = 6.92 µg mL−1);
ABTS (IC50 = 2.35 µg mL−1)
Talaromyces islandicus (EN-501) isolated from Laurencia okamurai [59]
1,4,5-Trihydroxy-2-methylxanthone (16) DPPH (IC50 = 1.23 µg mL−1);
ABTS (IC50 = 1.27 µg mL−1)
Norlichexanthone (17) DPPH (% Scavenging effect: 6.2% at 25.0 μg mL−1; 12.9% at 50 μg mL−1; 25.3% at 100 μg mL−1; 90.6% at 500 μg mL−1) Enteromorpha sp. collected at Fehmarn Island [81]
2,3,6,8-Tetrahydroxy-1-methylxanthone (28) DPPH (% Scavenging effect: 94.7% at 25.0 μg mL−1; 94.8% at 50 μg mL−1; 95.2% at 100 μg mL−1; 95.4% at 500 μg mL−1)
Linolenic acid peroxidation (% Inhibition: 17.0% at 7.4 μg mL−1; 37.0% at 37 μg mL−1)
Arthone C (43) DPPH (IC50 = 16.9 µM);
ABTS (IC50 = 18.7 µM)
Arthrinium sp. (UJNMF0008) [97]
2,3,4,6,8-Pentahydroxy-1-methylxanthone (44) DPPH (IC50 = 22.1 µM);
ABTS (IC50 = 18.0 µM)
Sterigmatocystin (81) ABTS (0.65 ± 0.13 TEAC values) Aspergillus versicolor (A-21-2-7) isolated from sediment collected in the South China Sea [98]
Oxisterigmatocystin C (93) ABTS (1.16 ± 0.18 TEAC values)
Oxisterigmatocystin D (120) ABTS (0.55 ± 0.13 TEAC values)

ABTS: (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)); DPPH: (2,2-diphenyl-1-picryl-hydrazyl-hydrate); IC50: Half maximal inhibitory concentration; TEAC: Trolox equivalents antioxidant capacity.