Table 2.
Mean diameter, polydispersity index, zeta potential, and encapsulation efficiency of NLC formulations on day 0. Values are expressed as the mean ± SD (n = 3).
| Mean Diameter (nm) 1 | Polydispersity Index 1 | Zeta Potential (mV) 1 |
Encapsulation Efficiency (%) 2 | |
|---|---|---|---|---|
| NLC Placebo | 180.3 ± 6.3 a | 0.216 ± 0.023 b | 16.97 ± 4.98 b | — |
| NLC Riluzole | 208.5 ± 5.0 a,b | 0.154 ± 0.023 a | 20.67 ± 2.11 b | 98.70 ± 0.96 a |
| Functionalized NLC | 221.9 ± 18.1 b | 0.219 ± 0.027 b | −16.41 ± 0.31 a | 94.21 ± 4.35 a |
1 Data were analyzed using Tukey’s HSD test, with different letters (a,b) representing statistically significant differences (p < 0.05) between the different formulations. 2 Data were analyzed using the t-Student’s test (statistical significance was considered for p < 0.05).