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Histological changes in the kidneys in mice (HE. 200×). (A–D). Typical histological picture of mice suffering from different doses of FB1 for 2, 4, 6 and 8 weeks; 2 weeks (n = 5), 4 weeks (n = 6–7), 6 weeks (n = 5), and 8 weeks (n = 9). FB1-1 indicates 0.018 mg/kg BW, FB1-2 indicates 0.054 mg/kg BW, FB1-3 indicates 0.162 mg/kg BW, FB1-4 indicates 0.486 mg/kg BW, FB1-5 indicates 1.458 mg/kg BW and FB1-6 indicates groups 4.374 mg/kg BW.
