Table 1.

Lesional score of the kidneys in mice exposed to different levels of FB1 for 2, 4, 6 and 8 weeks.

2 Weeks	Control	FB1-1	FB1-2	FB1-3	FB1-4	FB1-5	FB1-6
Glomerulus	0.00 ± 0.00	0.00 ± 0.00	0.33 ± 0.58	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.67 ± 0.58
Renal tubule	0.00 ± 0.00	0.33 ± 0.58	0.67 ± 0.58	1.00 ± 0.00	1.00 ± 1.00	0.67 ± 0.58	1.00 ± 0.00
Intestitial inflammation	0.00 ± 0.00	0.00 ± 0.00	1.33 ± 0.58 *	1.33 ± 0.58 *	0.67 ± 0.58	1.00 ± 0.00	2.00 ± 0.00
4 Weeks	Control	FB1-1	FB1-2	FB1-3	FB1-4	FB1-5	FB1-6
Glomerulus	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.33 ± 0.58	0.00 ± 0.00	0.00 ± 0.00
Renal tubule	0.00 ± 0.00	0.67 ± 0.58	1.00 ± 0.00	1.00 ± 0.00	0.67 ± 0.58	1.33 ± 0.58 *	0.67 ± 0.58
Intestitial inflammation	0.00 ± 0.00	0.00 ± 0.00	1.00 ± 0.00	0.67 ± 0.58	0.67 ± 0.58	0.33 ± 0.58	1.00 ± 0.00
6 Weeks	Control	FB1-1	FB1-2	FB1-3	FB1-4	FB1-5	FB1-6
Glomerulus	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.67 ± 0.58	0.67 ± 0.58	0.67 ± 0.58	0.67 ± 0.58
Renal tubule	0.00 ± 0.00	0.67 ± 0.58	0.33 ± 0.58	1.00 ± 0.00	1.33 ± 0.58 *	0.67 ± 0.58	1.33 ± 0.58 *
Intestitial inflammation	0.00 ± 0.00	0.33 ± 0.58	1.00 ± 0.00	0.67 ± 0.58	0.00 ± 0.00	0.33 ± 0.58	0.67 ± 0.58
8 Weeks	Control	FB1-1	FB1-2	FB1-3	FB1-4	FB1-5	FB1-6
Glomerulus	0.00 ± 0.00	0.00 ± 0.00	0.67 ± 0.58	0.67 ± 0.58	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00
Renal tubule	0.00 ± 0.00	1.00 ± 0.00	0.67 ± 0.58	1.33 ± 0.58 *	1.00 ± 0.00	1.00 ± 0.00	1.67 ± 0.58 *
Intestitial inflammation	0.00 ± 0.00	0.00 ± 0.00	0.33 ± 0.58	0.67 ± 0.58	0.00 ± 0.00	0.33 ± 0.58	1.00 ± 0.00

Values are shown as the mean ± SEM; 2 weeks (n = 5), 4 weeks (n = 6–7), 6 weeks (n = 5), and 8 weeks (n = 9). FB1-1 indicates 0.018 mg/kg BW, FB1-2 indicates 0.054 mg/kg BW, FB1-3 indicates 0.162 mg/kg BW, FB1-4 indicates 0.486 mg/kg BW, FB1-5 indicates 1.458 mg/kg BW and FB1-6 indicates groups 4.374 mg/kg BW; Values are shown as the mean ± SEM; 2 weeks (n = 5), 4 weeks (n = 6–7), 6 weeks (n = 5), and 8 weeks (n = 9); * indicates p < 0.05 vs. control group.