Figure 2.
CBG and CBD protect against chemical and bacteria-induced inflammation. Primary NHEKs were cultured in the presence of CBD or CBG for 1 h. Later, cells were co-treated with compounds and 5 ng/mL TPA or 1 × 107 CFU C. acnes (ATCC® 6919™) for 24 h. Media supernatants were collected after 24 h and analyzed by ELISA for (a) Interleukin-8 (IL-8) or (b) Interleukin-1β (IL-1β). Data represent mean ± SE from three independent experiments. * p < 0.05; ** p ≤ 0.01 relative to inducer + vehicle group.