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Skin irritancy was improved by 0.1% CBG in serum formulation as measured by visual grading. (a) Visual grade data represent mean ± SEM from 20 participants from each group. * p < 0.05; ** p ≤ 0.01 indicates a statistically significant difference compared to untreated group. (b) Photographs of a representative subject on day 1, 7, and 14 of the study where patch 1 = Untreated; 2 = 0.1% CBG; and 3 = Vehicle (placebo).
