Fig. (5).
Major post-translational modifications of histones. Abbreviations: HATs, histone acetyltransferases; HDCAs, histone deacetylases; HMTs, histone methylases; K7R-DMs, histone demethylases. S, serine; K, lysine; R, arginine; Y, tyrosine. The inset shows the main modifications observed on histone 3. S(10)-P is a phosphorylated serine situated at position tenth; K(9)-M/A is lysine at position ninth that can be methylated or acetylated (see text for details) [84-90]. (A higher resolution/colour version of this figure is available in the electronic copy of the article).