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CXCR7 agonist inhibits phosphorylation of Erk. Osteoclast precursors were incubated with RANKL, TNF-α, CXCL12 and CXCR7 agonist. Cells were lysed and the contents were analyzed by immunoblotting using the following antibodies: (A) p-Erk and Erk, (B) p-p38 and p38, and (C) p-JNK and JNK. CXCR7, C-X-C receptor 7; CXCL12, C-X-C motif chemokine ligand 12; RANKL, receptor activator of NF-κB ligand; TNF-α, tumor necrosis factor-α; p-, phosphorylated.
