Figure 3.

The 2$\times$P and 2$\times$YP bioreactor cultivation results. The initial concentration of peptone (2×P) and both yeast extract and peptone (2$\times$YP) in the YPG media were doubled in LRS6 cultivations. Temperature (×), pH (o) and dissolved oxygen ($\diamond$) were monitored and controlled online. Biomass (+), galactose ($\square$) and ethanol ($\Delta$) concentration were monitored via offline sampling twice daily for 2$\times$P (A) and 2$\times$YP (C) cultivations. The taxane concentration was measured via the GCMS analysis of dodecane samples taken twice daily for 2$\times$P (B) and 2$\times$YP (D).