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. 2021 Dec 29;14(1):76. doi: 10.3390/pharmaceutics14010076

Table 1.

Physiochemical properties of cysteine endopeptidases derived from pineapple plants [1,13,15,22,23,24].

Stem Bromelain Fruit Bromelain Ananain Comosain
Source Pineapple stem Pineapple fruit Pineapple stem Pineapple stem
Molecular weight [kDa] 23.8–37.0 23.0–32.5 23.4–25.0 24.4–24.5
Isoelectric point ≥9.5 4.6 >10 >10
Amino acid sequence 212, 291, 285 326, 351 216 186
Optimum T [°C] 40–60 37–70 / /
Optimum pH 4–8 3–8 / /
Presence of Glycoproteins Yes Yes/No No Yes