Table 3.
Primary structures of nisin natural analogues. The changes in amino acids compared to nisin A are highlighted in yellow (not valid for Nisin J).
|
Natural nisin analogues represented with a primary structure (Reproduced with permission from [147,155], ASM Journals, Washington, USA, 2020 and Springer Nature, London, UK, 2020) |
Production strain [7,155] |
Molecular weight [Da] [147] | |
| Nisin A |
|
Lactococcus lactis (dairy products) | 3354 |
| Nisin Z |
|
Lactococcus lactis NIZO 22,186 (dairy products) | 3331 |
| Nisin F |
|
Lactococcus lactis F10 (fish gut) | 3315 |
| Nisin Q |
|
Lactococcus lactis 61–14 (Japanese river water) | 3327 |
| Nisin H |
|
Streptococcus hyointestinalis (porcine intestine) | 3453 |
| Nisin O A1-A3 |
|
Blautia obeum A2–162 (human gastrointestinal tract) | 3546 |
| Nisin O A4 |
|
Blautia obeum A2–162 (human gastrointestinal tract) | 3259 |
| Nisin U |
|
Streptococcus uberis 42 (bovine mammary secretions) | 3029 |
| Nisin U2 |
|
Streptococcus uberis D536 (bovine mammary secretions) | 3015 |
| Nisin P |
|
Streptococcus gallolyticus subsp. Pasteurianus (alimentary tract of ruminants) | 2989 |
| Nisin J |
|
Staphylococcus capitis APC 2923 (human skin) | 3458 |