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Interaction between SARS-CoV-2 and host cell. The SARS-CoV-2 virion is composed of 4 structural proteins, spike protein (S), membrane protein (M), envelope protein (E), and nucleocapsid protein (N), associated with single-stranded RNA (ssRNA) of the virion. S protein interacts with the host cell ACE2 protein and is activated by TMPRSS2 as part of the infection mechanism.
