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. 2021 Dec 24;14(1):33. doi: 10.3390/v14010033

Figure 2.

Figure 2

Single intratracheal phage application reduced bacterial burden in mice. Colony forming units (CFU) of A. baumannii were quantified in BAL, homogenized half lungs and spleen at 24 h (A) and 48 h (C) post infection (p.i.). Representative images of immunohistochemically stained lung tissue sections to visualize A. baumannii at 24 h (B) and 48 h p.i. (D). Data are expressed as single values with mean ± SD. CFU data were logarithmized (Y = log(CFU+1)) and tested with unpaired student’s t-test; n = 9–11 (24 h p.i.); n = 8–10 (48 h p.i.) for each group. * p < 0.05 between indicated groups; n = 3–4 (sham-infected groups), n = 6 (A. baumannii infected groups) per time point for histology. #: neutrophils, arrowheads: bacteria, scale bar 50 μm.