Table 3.

Parameters for solute transport employed in drug delivery modeling.

Symbol	Definition	Value [unit]	Reference
DF	Drug diffusion coefficient	$3.4 \times {10}^{-6} \left[{\mathrm{cm}}^2/\mathrm{s}\right]$	[60]
P	Microvessel permeability coefficient	$3 \times {10}^{-4} \left[\mathrm{cm}/\mathrm{s}\right]$	[61]
KON	Constant of binding rate	$1.5 \times {10}^3 \left[{\mathrm{M}}^{-1}·{\mathrm{s}}^{-1}\right]$	[54]
KOFF	Constant of unbinding rate	${8 \times 10}^{-3} \left[{\mathrm{s}}^{-1}\right]$	[54]
KINT	Constant of cell uptake rate	${5 \times 10}^{-5} \left[{\mathrm{s}}^{-1}\right]$	[54]
φ	Tumor volume fraction accessible to drugs	0.3	[54]
Crec	Concentration of cell surface receptors	${1 \times 10}^{-5} \left[\mathrm{M}\right]$	[54]
ω	Cancer cell survival constant	$0.6603 \left[{\mathrm{m}}^3/\mathrm{mol}\right]$	[62]
KEL	TSL release rate at 42 ºC	$0.05409 \left[{\mathrm{s}}^{-1}\right]$	[55]