Table 2.
Organ System/Parameter | 1 Point | 2 Points | 3 Points | 4 Points | |
---|---|---|---|---|---|
Respiratory/ PaO2/FiO2 [mmHg] |
<400 | <300 | <200 with respiratory support |
<100 with respiratory support |
|
Cardiovascular/ Hypotension |
MAP <70 mmHg |
nor-/epinephrine ≤ 0.05 µg/kg/min | nor-/epinephrine ≤ 0.1 µg/kg/min |
nor-/epinephrine ≥ 0.1 µg/kg/min
or multiple vasopressors |
|
Coagulation/ Platelets [×103/mm3] |
<150 | <100 | <50 | <20 | |
Renal/ Creatinine or urine output |
1.2–1.9 mg/dL (110–170 µmol/L) |
2.0–3.4 mg/dL (171–299 µmol/L) |
3.5–4.9 mg/dL (300–440 µmol/L) or <500 mL/day |
≥5 mg/dL (>440 µmol/L) or <200 mL/day |
|
Metabolism/ Hyperglycaemia (without history of diabetes mellitus) |
plasma glucose > 200 mg/dL (untreated) | >25%/24 h increase of insulin/h i.v.drip | >50%/24 h increase of insulin/h i.v.drip | persistent plasma glucose > 200 mg/dL despite insulin bolus + continuous therapy | |
patient non-sedated | CNS/Glasgow Coma Scale (points) | 13–14 | 10–12 | 6–9 | <6 |
patient sedated | intestines/enteral feeding intolerance | distended abdomen | gastric residual volume of 100% of feeding rate | gastric residual volume of 200% of feeding rate or inability of gastric feeding > 24 h | inability of gastric feeding > 48 h |