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. 2021 Dec 31;10(1):86. doi: 10.3390/microorganisms10010086

Figure 6.

Figure 6

Loss of CbrR expression leads to a defect in host cell adherence and invasion. Assessment of WT, cbr−R, and cbrR+ strains to attach and invade host cells was determined by infecting human epithelial INT407 cells with each of the strains. WT and cbrR− cells attached and invaded cells at similar rates, whereas cbrR+ cells showed deficiencies in both adherence and invasion compared to both WT and cbrR− (* p < 0.05; ** p < 0.01). Statistical significance was determined by a one-way ANOVA with Tukey’s multiple comparisons test (GraphPad Prism 9, San Diego, CA, USA). Experiments were performed three times in triplicate.