Table 1.
Batches | Component (% w/v) | Drug Content (mg/5 mL of nPEVs) * | % EE * | Particle Size (nm) * | PDI * | Zeta Potential (mV) * | ||
---|---|---|---|---|---|---|---|---|
ITZ | Lipid | Cholesterol | ||||||
S1 | 1 | 4 | - | 95.36 ± 0.31 | 95.36 ± 0.51 | 196.55 ± 0.025 | 0.092 ± 0.03 | +11.1 ± 0.52 |
S2 | 1 | 4 | 2 | 96.59 ± 0.44 | 96.59 ± 0.44 | 221.2 ± 0.056 | 0.19 ± 0.045 | +17.2 ± 0.35 |
S3 | 1 | 7 | 3 | 98.43 ± 0.32 | 97.22 ± 0.46 | 240.33 ± 0.016 | 0.38 ± 0.01 | +19.1 ± 0.87 |
S4 | 2 | 7 | 3 | 193.89 ± 0.8 | 96.94 ± 0.70 | 252.2 ±0.019 | 0.49 ± 0.011 | +22.5 ± 0.28 |
* Each value represents mean, n = 3 ± SD.