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. 2022 Jan 14;9(1):28. doi: 10.3390/jcdd9010028

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© 2022 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Example snapshots of 2-dimensional tissue simulations showing the effects of ionic current alteration on reentrant waves. (A–D) The effects of ionic current perturbations (25% I_Kur, 300% I_Kr, 300% I_K1 and AF electrical remodeling) on reentry in the Courtemanche human atrial cardiomyocyte model. (E–G) The effects of ionic current alterations (300% I_to, 25% I_CaL and 300% I_Kur) on reentry in the Grandi human atrial cardiomyocyte model. The right panels show the rotor-core trajectories tracked up to 3000 ms.