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. 2022 Jan 1;14(1):28. doi: 10.3390/toxins14010028

Table 4.

Effect of non-bioaccessible mycotoxins on the maximal optical density (MOD), growth rate, and lag time of Lactobacillus casei BL23 and Bifidobacterium lactis ATCC 27536 strains. Data are presented as the mean ± SD of four replicates (n = 4). Differences between meals with mycotoxins (AFB1, OTA, or MIX) in relation to the control meal are indicated as * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001.

Lactobacillus casei
NBIO AFB1 OTA MIX Control
0.5% MOD 3.128 ± 0.036 3.114 ± 0.034 3.176 ± 0.040 3.132 ± 0.023
Growth rate
(μmax) (h−1)
0.4502 ± 0.014 0.4574 ± 0.014 0.453 ± 0.015 0.4735 ± 0.010
Lag time (h) 5.29 ± 0.137 5.228 ± 0.131 5.326 ± 0.149 5.298 ± 0.088
1% MOD 3.23 ± 0.038 3.235 ± 0.024 3.122 ± 0.052 * 3.202 ± 0.032
Growth rate
(μmax) (h−1)
0.3527 ± 0.009 **** 0.5211 ± 0.011 *** 0.3659 ± 0.014 **** 0.4555 ± 0.012
Lag time (h) 4.92 ± 0.147 ** 5.44 ± 0.084 4.863 ± 0.210 ** 5.39 ± 0.121
2% MOD 2.364 ± 0.169 *** 3.104 ± 0.026 ** 2.946 ± 0.061 2.924 ± 0.059
Growth rate
(μmax) (h−1)
0.131 ± 0.006 **** 0.3696 ± 0.007 **** 0.228 ± 0.006 0.24 ± 0.007
Lag time (h) 1.141 ± 1.049 *** 5.383 ± 0.103 ** 4.308 ± 0.258 4.398 ± 0.256
Bifidobacterium lactis
NBIO AFB1 OTA MIX Control
0.5% MOD 7.078 ± 0.025 * 6.788 ± 0.041 *** 7.013 ± 0.030 7.014 ± 0.026
Growth rate
(μmax) (h−1)
0.7646 ± 0.006 0.7319 ± 0.009 0.7569 ± 0.007 0.764 ± 0.006
Lag time (h) 5.858 ± 0.044 5.808 ± 0.074 5.844 ± 0.053 5.88 ± 0.046
1% MOD 7.078 ± 0.025 * 6.788 ± 0.041 **** 7.013 ± 0.030 7.014 ± 0.026
Growth rate
(μmax) (h−1)
0.7646 ± 0.006 0.7319 ± 0.009 ** 0.7569 ± 0.007 0.764 ± 0.006
Lag time (h) 5.858 ± 0.044 5.808 ± 0.074 5.844 ± 0.053 5.88 ± 0.046
2% MOD 5.585 ± 0.042 **** 6.224 ± 0.058 *** 6.095 ± 0.087 5.978 ± 0.050
Growth rate
(μmax) (h−1)
0.5585 ± 0.008 **** 0.6715 ± 0.013 0.6742 ± 0.021 0.6902 ± 0.013
Lag time (h) 5.689 ± 0.092 **** 6.281 ± 0.115 * 6.289 ± 0.173 6.515 ± 0.101