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. 2022 Jan 3;12(1):62. doi: 10.3390/life12010062

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The QTE analysis of the CITRIS-ALI trial. The horizontal axis shows the quantile of survival. The vertical axis shows the difference in the life span between the vitamin C and placebo groups on the same quantile. The blue line shows the QTE estimate and the shaded region shows its 95% CI. This QTE analysis was carried out with the cqr program of the quantreg package of R [131]. The extraction of the CITRIS-ALI trial data has been described previously [116]. See Listing S4 for the calculation in the Supplementary Materials.