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. 2022 Jan 3;12(1):62. doi: 10.3390/life12010062

Table 4.

Errors in Chalmers’ presentation of the Karlowski (1975) trial results.

Ascorbic Acid Placebo
No. of Subjects Mean Duration (Days) No. of Subjects Mean Duration (Days) Difference in Duration (Days)
Chalmers (1975) review [82]:
Karlowski (1974) 101 6.80 89 6.30 +0.50
Correct data [33,34]:
Karlowski (1975) 57 5.92 46 7.14 −1.22 (p = 0.046)

In the Chalmers (1975) review, half of the Karlowski (1975) trial “placebo group” participants were actually vitamin C participants (43 of the 89). The common cold duration in Chalmers’ “placebo” group was actually the mean of two vitamin C groups [86]. Correct data shows the findings for the 3 + 3 g/day and 0 + 0 g/d (placebo) groups. All four groups are shown in Figure 1, and analyzed in [47].