Table 4.
Ascorbic Acid | Placebo | ||||
---|---|---|---|---|---|
No. of Subjects | Mean Duration (Days) | No. of Subjects | Mean Duration (Days) | Difference in Duration (Days) | |
Chalmers (1975) review [82]: | |||||
Karlowski (1974) | 101 | 6.80 | 89 | 6.30 | +0.50 |
Correct data [33,34]: | |||||
Karlowski (1975) | 57 | 5.92 | 46 | 7.14 | −1.22 (p = 0.046) |
In the Chalmers (1975) review, half of the Karlowski (1975) trial “placebo group” participants were actually vitamin C participants (43 of the 89). The common cold duration in Chalmers’ “placebo” group was actually the mean of two vitamin C groups [86]. Correct data shows the findings for the 3 + 3 g/day and 0 + 0 g/d (placebo) groups. All four groups are shown in Figure 1, and analyzed in [47].