Table 3.
Renal Cell Types | Biomarkers | References | |
---|---|---|---|
Protein markers | m-RNA markers | ||
Podocytes | Wilms tumor-1 Nephrin Podocin Podocalyxin Synaptopodin |
NPHS1 NPHS2 Synaptopodin Wilms tumor-1 Podocalyxin |
[18] [88] [89] [23] [90] |
Proximal tubules | Lotus tetragonolobus lectin Aquaporin-1 (AQP1) Cadherin 6 Jagged 1 Megalin Kidney injury molecule 1 |
ABCC1 ABCC3 ABCC4 SLC22A3 SLC40A1 |
[18] [88] [89] |
Loop of Henle | Cadherin 1 Uromodulin |
Claudin 10 Claudin 14 SLC12A1 Uromodulin |
[18] [91] [92] [89] |
Distal tubules | Pterin-4 alpha-carbinolamine dehydratase 1 Solute carrier family 41 member 3; Cadherin 1 Brn1 Na+/Cl– cotransporter GATA Binding Protein 3 |
Pterin-4 alpha-carbinolamine dehydratase 1 Solute carrier family 41 member 3; Cadherin 1 SLC12A3 Calbindin 1 |
[18] [88] [89] |
Collecting ducts | Dolichus biflorisagglutinin Aquaporin-2 (AQP2) Aquaporin-3 (AQP3) |
Cadherin 1 GATA Binding Protein 3 Aquaporin-3 |
[23] [89] |
Endothelial cell | Platelet and endothelial cell adhesion molecule 1 Cadherin 5 Fms related receptor tyrosine kinase 1 Cluster of differentiation 34 Cluster of differentiation 31 |
Platelet and endothelial cell adhesion molecule 1 Cadherin 5 Fms related receptor tyrosine kinase 1 CD34 |
[23] [93] [89] [94] |
Mesangial cells | Platelet-derived growth factor receptor beta Insulin like growth factor binding protein 5 Transgelin Matrix metallopeptidase 2 |
Actin alpha 2, smooth muscle Collagen type I alpha 1 chain Transgelin |
[23] [95] |
Abbreviations: ABCC1, ATP-binding cassette sub-family C member 1; SLC22A3, Solute carrier family 22 member 3.