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. 2022 Jan 14;23(2):905. doi: 10.3390/ijms23020905

Table 1.

The 2010 ACR/EULAR classification criteria for RA.

Classification Criteria for RA (Total Score ≥ 6 is Considered Satisfactory for the Diagnosis of RA) Score
joint involvement
(swollen or tender joint)
1 large joint (shoulders, elbows, hips, knees, and ankles) 0
2–10 large joints 1
1–3 small joints (with or without involvement of large joints) * 2
4–10 small joints (with or without involvement of large joints) 3
>10 joints (at least 1 small joint) ** 5
serology Negative RF and negative ACPA (≤upper limit of normal (ULN)) 0
Low-positive RF or low-positive ACPA (≤ULN and ≤3 times) 2
High-positive RF or high-positive ACPA (≤3 times) 3
acute-phase reactants Normal CRP and normal ESR 0
Abnormal CRP or abnormal ESR 1
duration of symptoms <6 weeks 0
≥6 weeks 1

CRP = C-reactive protein; ESR = erythrocyte sedimentation rate. * “Small joints” refers to the metacarpophalangeal joints, proximal interphalangeal joints, second through fifth metatarsophalangeal joints, thumb interphalangeal joints, and wrists. ** In this category, at least 1 of the involved joints must be a small joint; the other joints can include any combination of large and additional small joints, as well as other joints not specifically listed elsewhere (temporomandibular, acromioclavicular, sternoclavicular, etc.).