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The expression level changes of (A) caspase-3; (B) caspase-9; (C) cyclin-D; (D) cyclin-E; (E) MMP-2; (F) MMP-9 genes in MDA-MB-231 cancerous cell line after 72 h treatment by co-loading Let and Cyclo in different niosomal formulations at their IC50 concentration (* p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001).
