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. 2022 Jan 11;11(2):336. doi: 10.3390/jcm11020336

Table 2.

Important Variable Selection with Boruta Algorithm.

Variable Mean Imp Median Imp Min Imp Max Imp Norm Hits Decision
Lactate (mmol/L) 32.77 32.68 29.04 35.91 1 Confirmed
Bicarbonate (mmol/L) 19.92 20.04 16.59 23.41 1 Confirmed
Surgery prior to admission 12.3 12.21 9.24 15.16 1 Confirmed
Sepsis/septic shock 6.79 6.64 4.79 10.19 1 Confirmed
Creatinine (μmol/L) 6.28 6.24 3.51 8.32 1 Confirmed
Non-traumatic neurological disease 5.77 5.79 2.76 7.79 1 Confirmed
Chronic liver disease 5.05 5.19 2.27 8.23 0.93 Confirmed
Admission type (planned) 4.78 4.79 1.37 7.37 0.95 Confirmed
Sodium (mmol/L) 4.18 4.19 2.17 7.02 0.86 Confirmed
APACHE IV 3.97 3.95 1.16 7 0.87 Confirmed
Chronic kidney failure 3.46 3.35 0 6.2 0.76 Confirmed
Hx of organ transplantation 3.22 3.22 0.37 5.58 0.71 Confirmed
Mechanical ventilation (at admission) 3.14 3.23 −0.68 5.15 0.7 Confirmed
Hx of malnutrition 2.9 2.96 −0.2 5.41 0.68 Confirmed
Heart failure/cardiogenic shock 2.54 2.69 −0.3 4.36 0.54 Tentative
Sex (male) 1.41 1.21 −0.93 3.38 0.04 Rejected
Hx of immune deficiency −0.03 −0.13 −3.17 2.26 0.01 Rejected
Major trauma −0.13 −0.49 −1.46 1.54 0 Rejected

Variable selection for contribution to FO on day three after ICU admission. History of (Hx). The laboratory markers lactate, sodium, bicarbonate, creatinine, and the APACHE IV score were measured at admission (=baseline). Mean Imp—the mean of IMp, Median Imp—the median of IMp, Min Imp—the minimum of IMp, Max Imp—the maximum of IMp, Norm Hits-the number of hits normalized to number of importance source runs, where. IMp is the importance measure computed over multiple iterations.