Table 2.

Univariate (A) and multivariate (B) logistic regression of cofactors associated with the plasma pCS concentration.

A
Crude Model
Plasma pCS Concentration (µg/mL)
	OR (95%CI)	p- Value
Age (years)	1.03 (1.02; 1.05)	<0.0001
BMI (kg/m2)	1.02 (0.98; 1.06)	0.245
Sex (male)	1.25 (0.84; 1.87)	0.276
Time since transplantation (months)	1.002 (1.000; 1.004)	0.088
Albumin (g/L)	0.95 (0.91; 1.00)	0.065
At least one OAT1/OAT3 inhibitor	2.23 (1.38; 3.65)	0.001
eGFR (mL/min)	0.96 (0.95; 0.97)	<0.0001
B
Plasma pCS Concentration (µg/mL)
	OR (95%CI)	p -Value
Unadjusted
At least one OAT1/OAT3 inhibitor	2.23 (1.38; 3.65)	0.001
Model 1
At least one OAT1/OAT3 inhibitor	1.98 (1.21; 3.27)	0.007
Age (years)	1.03 (1.02; 1.05)	0.0002
Model 2
At least one OAT1/OAT3 inhibitor	1.99 (1.19; 3.35)	0.009
Age (years)	1.02 (1.01; 1.04)	0.005
eGFR (mL/min)	0.96 (0.95; 0.98)	<0.0001
Model 3
At least one OAT1/OAT3 inhibitor	2.04 (1.22; 3.47)	0.007
Age (years)	1.03 (1.01; 1.05)	0.002
eGFR (mL/min)	0.96 (0.95; 0.97)	<0.0001
Albumin (g/L)	1.04 (0.98; 1.11)	0.151
Model 4
At least one OAT1/OAT3 inhibitor	2.11 (1.26; 3.61)	0.005
Age (years)	1.03 (1.01; 1.05)	0.003
eGFR (mL/min)	0.96 (0.95; 0.97)	<0.0001
Albumin (g/L)	1.05 (0.99; 1.11)	0.123
Time since transplantation (months)	1.00 (1.00; 1.00)	0.401

BMI, body mass index; eGFR, estimated glomerular filtration rate; OR, odds ratio; pCS, para-cresyl sulfate.