Figure 1.

Primary human dermal fibroblast response to Cupuaçu extract treatment. (A) Cellular viability after 24 h incubation with different concentrations of Cupuaçu extract; (B) cellular proliferation for up to 7 days incubation with 100 μg/mL Cupuaçu extract. The graphs represent the absorbance mean value and standard deviation of three biological replicates in triplicates, normalized according to the 100% viability/proliferation positive controls. Positive controls received FBS supplementation and negative controls consisted of cells maintained without FBS supplementation. Statistical differences have been verified by two-way ANOVA test and Tukey post hoc test. * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.