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. 2022 Jan 3;14(1):108. doi: 10.3390/pharmaceutics14010108

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the arrangement of surfactants in the phospholipid bilayer and of their possible electrostatic interaction with the manganese ion, namely Mn²⁺ or Mn³⁺ (a) and macroscopic aspect of the produced liposomal suspensions before (b) and after extrusion (c), 1: plain-LP; 2: LP-SD; 3: LP-NLS; 4: LP-PAG; 5: LP-SLL.