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Schematic diagram for EV capture and release through the host guest interactions between β-cyclodextrin (β-CD) and 4-aminoazobenzene (AAB). The immunoaffinitive superparamagnetic nanoparticles (SNPs) are prepared by modification with AAB and then connection to β-CD-PEG2000-COOH. EVs in different samples are captured by immunoaffinitive SNPs and mildly eluted by adding the competitive host molecule, α-CD.
