Table 2.
Examples of gene reporter systems and their corresponding imaging probe.
Transgene | Imaging Probe | Clinical Trials/Applications |
---|---|---|
HSV-1-tk HSV-1-sr39tk | [123I]/[124I]/[131I]FIAU [18F]FHBG | Yes |
hSSTR2 | [111In]In-pentetreotide [68Ga]Ga-DOTATATE [68Ga]Ga-DOTATOC |
No |
hNIS | [211At]At−, [188Re]ReO4−, [124I]/[131I]I−, [18F]TFB |
Yes |
hNET | [123I]MIBG [18F]MFBG |
No |