Table 6.
Impact of CRME on the castor oil-induced enteropooling in mice.
| Treatment | MVSIC * (mL) | % Inhibition in MVSIC | MWSIC ** (g) | % Inhibition in MWSIC |
|---|---|---|---|---|
| Control | 0.71 ± 0.00 | - | 0.78 ± 0.00 | - |
| Loperamide | 0.23 ± 0.02 | 67.6 | 0.18 ± 0.01 | 77 |
| CRME (100 mg/kg) |
0.68 ± 0.00 | 4.23 | 0.71 ± 0.00 | 8.97 |
| CRME (200 mg/kg) |
0.61 ± 0.00 | 14.08 | 0.7± | 10.26 |
| CRME (400 mg/kg) |
0.18±0.00 | 74.6 | 0.17± | 78.2 |
* MVSIC: mean volume of the small intestinal content. ** MWSIC: mean weight of the small intestinal content. A significant reduction was caused by CRME in the MVSIC and MWSIC at the dose of 400 mg/kg b.w. compared to the control.