Table 2.
Observer-reported outcomes for 500-mg mebendazole chewable tablet compared with tablets regardless of treatment in children aged 2 to 4 years.
| Observer-Reported Outcomes |
500-mg Mebendazole Chewable Tablet (n = 182) |
Hard Tablet Regardless of Treatment (n = 71) |
Statistical Test |
|---|---|---|---|
| Result intake | |||
| Fully taken | 170 (93) a | 49 (69) | F b: p < 0.001 |
| Partly taken | 11 (6) | 22 (31) | |
| Not taken | 1 (1) | 0 (0) | |
| Patient reaction | |||
| Positive | 65 (36) | 13 (18) | χ2 c: p < 0.001 |
| Neutral | 91 (50) | 22 (31) | |
| Negative | 26 (14) | 36 (51) | |
|
Preparation and
administration time |
|||
| Short | 22 (12) | 9 (13) | χ2: p < 0.001 |
| Medium | 131 (72) | 24 (34) | |
| Long | 29 (16) | 38 (54) | |
| Divided dose | |||
| No divided dose | 163 (90) | 30 (42) | χ2: p < 0.001 |
| Use divided dose | 19 (10) | 41 (58) | |
| Food/drink d | |||
| No food/drink | 95 (52) | 18 (25) | χ2: p < 0.001 |
| Use food/drink | 87 (48) | 53 (75) | |
| Alteration e | |||
| No alteration | 152 (84) | 15 (21) | χ2: p < 0.001 |
| Use alteration | 30 (16) | 56 (79) | |
| Extra device f | |||
| No extra device | 152 (84) | 55 (77) | χ2: p = 0.35 |
| Use extra device | 30 (16) | 16 (23) | |
| Reward | |||
| No reward | 174 (96) | 36 (51) | χ2: p < 0.001 |
| Use reward | 8 (4) | 35 (49) | |
| Restraint | |||
| No restraint | 182 (100) | 59 (83) | χ2: p < 0.001 |
| Use restraint | 0 (0) | 12 (17) |
a n (%): number and percentages; b F: Fisher’s exact test; c χ2: Pearson’s chi squared test; d either mixed with the drug or taken just before or after administration; e modification of dosage form prior to administration; f device not provided with the medicine.