Table 4.
Sensitivity analyses.
| All | CKD Grade 3 | CKD Grade 2 | Normal eGFR | Hyperfiltration | Overall p-Value | |
|---|---|---|---|---|---|---|
| Diabetes N (%) | 503 (100) | 48 (9.5) | 244 (48.5) | 174 (34.6) | 37 (7.4) | |
| Initial MDRD | 86 (71; 100) | 52 (46.5; 55) | 77 (70; 83) | 100 (94; 108) | 132 (126; 136) | <0.01 |
| Final MDRD | 87 (74; 103) | 55 (46.5; 62.5) | 79 (72; 89) | 102 (89; 113) | 119 (110; 138) | <0.01 |
| Delta MDRD | 1 (−5; 10) | 2.5 (−1.5; 8.5) | 3 (−4; 10) | 0 (−10; 10) | −8 (−22; 5) | <0.01 |
| Hypertension N (%) | 1730 (100) | 148 (8.5) | 993 (57.3) | 518 (29.9) | 71 (4.1) | |
| Initial MDRD | 82 (70; 94) | 53 (48; 57) | 76 (69; 82.8) | 97 (93; 105) | 131 (124; 137) | <0.01 |
| Final MDRD | 85 (74; 98) | 57.5 (50; 64.5) | 80 (73; 88) | 101 (92; 110) | 125 (110; 138) | <0.01 |
| Delta MDRD | 3 (−3; 10) | 5 (0; 9) | 4 (−2; 11) | 0 (−6; 11) | −3 (−21; 3) | <0.01 |
| No diabetes and No hypertension N (%) | 1383 (100) | 50 (3.6) | 761 (55) | 515 (37.2) | 57 (4.1) | |
| Initial MDRD | 85 (76; 97) | 56 (53; 58) | 78 (72; 83) | 98 (93; 106) | 129 (123; 137) | <0.01 |
| Final MDRD | 89 (78; 101) | 63 (55; 67) | 82 (74; 89) | 100 (92; 110) | 118 (108; 132) | <0.01 |
| Delta MDRD | 3 (−4; 10) | 8.5 (1; 14) | 4 (−1; 11) | 0 (−7; 9) | −10 (−19; −1) | <0.01 |
| Weight loss period N (%) | 1243 (100) | 77 (6.2) | 647 (52) | 451 (36.2) | 70 (5.6) | |
| Initial MDRD | 86 (74; 98) | 55 (51; 58) | 78 (70; 83) | 99 (94; 107) | 130 (123; 136) | <0.01 |
| Final MDRD | 88 (77; 100) | 59 (52; 65) | 81 (73; 89) | 99 (91; 109) | 124 (114; 141) | <0.01 |
| Delta MDRD | 2 (−4; 10) | 5 (−1; 9) | 4 (−2; 10) | 0 (−8; 9) | −5 (−18; 4) | <0.01 |
Values are presented in median (interquartile range) or N (%). CKD, chronic kidney disease, eGFR: estimated glomerular filtration rate, MDRD: Modification of Diet in Renal Disease. P value: Kruskal–Wallis tests to compare four groups.