Table 1.
Alterations in epigenetic indicators in smoking normozoospermic men
| Parameters | N | SN |
|---|---|---|
| Cigarette pack yearsa | 0 | 15.00 ± 2.64 |
| Age (years) | 32.54 ± 0.60 | 34.13 ± 0.99 |
| Sperm density (× 106 cells/mL) | 99.23 ± 10.54 | 91.53 ± 10.91 |
| Semen volume (mL) | 2.77 ± 0.18 | 2.93 ± 0.27 |
| Sperm vitality (%) | 85.54 ± 1.99 | 86.04 ± 1.47 |
| Sperm motility (%) | 63.00 ± 2.38 | 57.96 ± 2.17 |
| Semen ROS (U/L) | 1515 ± 520 | 3807 ± 912* |
| Sperm histone-transition abnormality | 9.98 ± 0.88 | 12.92 ± 1.03* |
| Methylation level of sperm DNA (%) | 1.94 ± 0.16 | 2.44 ± 0.16* |
Data are presented as means ± SEM
N normozoospermic men who did not smoke; SN normozoospermic men who smoke heavily. aCigarette pack years was calculated by multiplying smoking dose (packs per day) by duration (years of smoking)
*p < 0.05 compared to the N group