Table 3.
Mathematical modelling and drug release kinetics from matrices.
Determination Coefficients for Mathematical Models | ||||||||
---|---|---|---|---|---|---|---|---|
Higuchi | Korsmeyer– | Zero- | First- | Weibull | Included Time Interval (min) |
|||
Peppas | Order | Order | ||||||
Sample | R 2 | R 2 | Release Exponent n |
R 2 | R 2 | R 2 | b | |
M125 | 0.9572 | 0.9983 | 0.515 | 0.2929 | 0.9801 | 0.9979 | 0.73 | 540 |
M100 | 0.921 | 0.9928 | 0.485 | 0.1304 | 0.9865 | 0.9983 | 0.78 | 540 |
M75 | 0.9375 | 0.9924 | 0.508 | 0.26 | 0.9906 | 0.9975 | 0.82 | 540 |
N125 | xx | 0.99 | 0.307 | xx | 0.8842 | 0.9965 | 0.52 | 240 |
N100 | 0.8125 | 0.9924 | 0.561 | xx | 0.9902 | 0.9955 | 0.89 | 240 |
N75 | 0.8821 | 0.9899 | 0.573 | 0.1626 | 0.9948 | 0.9944 | 1.01 | 240 |
N75M50 | 0.9916 | 0.9991 | 0.568 | 0.6066 | 0.9861 | 0.9997 | 0.73 | 720 |
N50M50 | 0.9963 | 0.9978 | 0.543 | 0.6602 | 0.9832 | 0.9999 | 0.66 | 720 |
N25M50 | 0.9821 | 0.9915 | 0.494 | 0.5366 | 0.9885 | 0.999 | 0.77 | 720 |